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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dc555a9b923c8931199b662730ccac20629e8c27e2145ad255ab464375862cbd' 
  AND token = 'gTDAkLcG7r+V8GaYtAXz//164+obc01Msw61/L22XsU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}