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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '46534880cbde6c2091577bfc3a9a222eedc756ead3f81fbbe2773fdcccd67fe4' 
  AND token = '/M93ndgDjg7smVUov2SkOTtLay/aV0bI7S1/nTwRgQI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}