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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '152847b4fca47b52883d19d2457f13bb0f7d0e151e604dbc7066384cd9d5feb0' 
  AND token = 'r2h9m81RiEEcH9uPkGpfdTl+3DwMSDa5887AJtPyGto=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}