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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bc649cd5b423ac5561165e427fb965025e6419b1c77936a82886fc7e349c8c2e' 
  AND token = 'bKnSlpvSUgek2/i3MK8kj+b6Xjbwz3yFxXoe92Vlu/Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}