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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c870fc4cec89cb643961820f520cecfdd17c52180b6b2b61ce66a6e636b402ab' 
  AND token = 'KYYn2gBnpzRt0/hbTixSLphDRU+m/25AO9HoS6dIrtU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}