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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b3b9bdb3d0d123dbc7c7e1d53e5b9589b56c348573a1af062806365d465c3af4' 
  AND token = 'bNNZlLO0j2mc40e2oh5M+OJmIyQdlAsgmReAwGRbpeY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}