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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '28bd5a29a2b0fc3783638b3cbe39edacf944970c83acf385ab908b43bc1bf777' 
  AND token = 'efD81bEVe6H7HslVWqgBS7vaXsNpZH9oMrx3+Cr+yCs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}