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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6657a648abd71fc995b885c8379055c6f8eecaf69f4e5266c018214e0cd07e69' 
  AND token = 'aGShPtv4TMt/EK8jZTjsQVFQOoFRfC+4TgyIkEIsjFc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00119

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}