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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '723b84dbb7134531e2aef54733075a510ac560cbf1aec916ce820c945d4e62d7' 
  AND token = 'JaCXX1MNE15PYmnVe0zcfnrT0HcYO6nxFZfxB8kJfYU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}