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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e0e190bdb3fd93bb748e1c5a66bc38465a8c58e0bba36b1e68f4d8963feaa787' 
  AND token = 'jycPWieIvi+9i8PUV7MT2Lyjverfdm5KIWgvGP1DgIA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}