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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fbcf6a542996fc6774c422740b47f276951d3aaa5c8732b464fffc4a16ea1e25' 
  AND token = '8PKkSWsChb6T9CjaqTki90EV+BTpSTgazLi4YlxYoXI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}