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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c3cae0100ff2439c38d6f871226885bdde0b332a175283bb4b24383d17d3000f' 
  AND token = 'SKzPqVKSRVpaRRi0bX60Iy0j2Isy0XDeEOpOsEhz+aw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}