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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '171eab0ea1ebc89f5e906eb6c807f2c89252afa08182e1ab8555957c3917d184' 
  AND token = 'ZJpDlbHMqSL9bXpC8xFFYCpqxxe9B/jCeoiXXXeDeEA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}