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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '78f79aedee14343835a23adc0ae9166b77b24bb5f74cc9fc5b8425574164f899' 
  AND token = '3amZQCrgpxvm/p3p2cceai3o4NTGiutdTG0kct2qwFM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}