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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a5bcbba7654c04ec9624047e8013b51329ee066567e1d9ceb165aac763a00226' 
  AND token = 'mwg/SGCRgh5mfL0rpBBRCKfmMN2cc6to+s5SegSqdpU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}