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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'eae2177925f3e834d7a5c8a5fac8d0c50ac64c9e9c45249884e563358ddc51c3' 
  AND token = 'u3AF6NiYCLvt1bkrX8cL+DWJYczhXeBdw8jFR5dEFQ0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}