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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4ea2b132395244756853d848614a5a3bcb175fb0faf9688c046c4480ed009206' 
  AND token = 'WU4Lqnn58FT4IsgBpjtdk76c2bBK7l7arxOnZtZ/5P0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}