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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5925f260e261ad2f6f4eb86138fe5414cc309e24f436d4074b9dce0ddadd3aab' 
  AND token = 'kEeTQg2/qKhqxG39E21LgETsnKI1XwiCRjldn0v6+E4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}