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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '610ec224d4a946ce60762aa342172aeff78a4edd3600999fa7ada654f6b6de21' 
  AND token = 'tGemNT0RvUPm0LJtqSp23ideBYWzbM8bmkMuVApw0Gs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}