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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5184741cc5b1078e2c6d549dccb59e0d5b13af548df9186deb22b38b4891bbfb' 
  AND token = '2t506TgtFCzk4taVJy2mZa+3sVET0V43t1AWVW0ZioU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}