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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6cf6046b6ba0454c0a3913188dc8f55b645b22b4ecec8232722599be27425c13' 
  AND token = 'l7DKGNCURcM3IXw8B/pO9Z6rG/745ZLe4ee7M0E9nC8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}