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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '506d5631bc3ab3acaf0f0e0fdbdcbd8510ae77d2e88c86a9cd406103bc5c453a' 
  AND token = 'qET6gwuM0/CRmw6Td7JMQVpsDncM+KDlgfbnLUN7q5Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}