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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8c876c51812ff87f7b56c51a9fdb9c15f991a059697978b89acf6bb8b46cb269' 
  AND token = 'pl6X7wfJw0Elx50DmIlTyWviy4kCt0QJnzr8E6rwLrs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00054

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}