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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0fdfb8bd96bf9e151d232ff485f4fcd8e4c37c0f39afc1136b07861fbbc9e01b' 
  AND token = 'iGxn1D2mEB9L0vxUnxn5KSFAnVZLM3oJR5Uoqx/gf78=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}