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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '22f9d91a62a4bb5a179920da734fc9cb7b10e96383c8c02fdf21f8096666b9fe' 
  AND token = 'jtHzvRO5XPo2OV+1GGwl0F9gKQN3tabIBniEd76frcs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00051

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}