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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f155d3f5177d10546997b1d0da2dcdda4df28eb180509cf838ed099e2930ef70' 
  AND token = 'pHitsHT+iPaya0M9YbtfDyl/K8wPiKnlzGl+SF2RUCQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00059

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}