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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6a2121f7b5e69c570828cb4f4c921004278e20bcc04c8fed3e3dc2de0e25c691' 
  AND token = 'E1ztn7OktdUjfgHDSz5ndC1SNEtHUDfiqMdbbk3Kw4o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}