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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '52c1a9946e5494779c8317233d70f833788bac785e17c8de84ed3b83af54d08b' 
  AND token = 'WR8CfhiiExb0F/i4MTwE12ENmSmpL/4A1qGHHzxDzqw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}