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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '49e4b03c40a82f3bdae88374d24afd3bb70da35979df0575f59d0a7009fa1ec3' 
  AND token = 'n4JlB+4UPr7k2nFSFmIHeJn12gTU7hRDKxP5aFOaTok=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00051

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}