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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7df8e4220cbfe623e7fadc48c4ad0a96ab24ba567bce50c1d7caaba101c2a226' 
  AND token = 'e6wS+43sdKCSE5gCQDmn5Ld/iVT6hb+Xxpr1HIuxJgI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}