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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2fd8a4ed7d475af1c159bd2809cd8b296d52bac71baee808b87ee05fa5647f17' 
  AND token = 'ETulB/ZTCmQ5pKkR2BkiDVSH8khVkvSfLZagxTOWQuU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}