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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c0c1436a0f8a28bdb6e411eeb416d3e31e1aa05d7e917c76003d8e72eb654bdf' 
  AND token = 'B1ZziHRKpDb0u/ErunigGinwWMrGCwhBLqdcWDv0iHs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}