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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '628f45f19f3c0b5bc9b0a857de2f36d45b9724d458a45260a998350415e9a19c' 
  AND token = 'IOm+hO10AMQEgyywp7oczwp4DPZL6I9zNegPK0L5QWc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}