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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '218108b2cdc0d0192f4a2f4c0ba83e839bc30d80f08b154b5f918d42dfa5053f' 
  AND token = 'Wu4p5PW4SKw2kNfr6WnNf5JoQoYNCB+wM/1t1tyW5v0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}