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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5a6c9e87a48c6880c2f4faefe1d6b3e30adc5b050424f0d8cea3343c85f8e6de' 
  AND token = '2gewILK4LzD3lnfSCOay8V4dG14Lnr3LRaeKS9no1PA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}