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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'de72d55272dc2cc536ab10db0ee4ea159e2306c1be4f138ea67d67122137e50a' 
  AND token = 'YzDA6dGWdzrJWc53V1c6QRd72+xbEWW4L0b/c520Q1U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}