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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '27e0b779d9051f1770781b590b42269e4ba75c2fbfba110966abf00d56a30dad' 
  AND token = 'gwewmia0QZUO0lNIwr63B7itMW/6k58c4FTZ5grImUg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}