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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e584bb01eef4a1cd73989262fb77228c92e73dfec12dfc3a36b70d3452547157' 
  AND token = 'fPV2ex+tEdF5jpUO81wQWLMs703vv1N9Y7Uj4f4htbI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00052

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}