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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3b0ceadcf739d50b0f578d719a5b99e42fab8efdad725e9b1ab5aaaf409546ab' 
  AND token = 'db0EMvAnJRvs+TLYT3hprIktdXeBvLxq/WoyMiWcEz8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}