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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ab046d0bde06a2e60bc508cc117d7e4f92fd5fb845e282f99561bc4650e4ab74' 
  AND token = 'C8HG1zP+FiYLkBma7gDpUYcZ8YtERmsDQGehCJLbly4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}