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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4f4148394a23891a79609c9dbc010db7e3a78c448e187a0bf06f3ca1c07cb059' 
  AND token = 'd3Ndx+e893Wmi9+Cs06dJJQR8zHX7aQkp7vKlKuTwgQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}