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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c191db50d1e6ce0389ff880dddf8fa5d8682792545b229befbc32ed40e5697d0' 
  AND token = '6HBXP3RKXkr6mJXQMhff6kg5iA3JymsMCRp7hKaZ4j8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}