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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'feb0486050d6eb0fad65ad717fbcb8311273a228c413715384b8c4e0d31799f3' 
  AND token = '11G3FAyHNDER06leqFWVzlCMKZc6B8nNcWNkhryJsYg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}