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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4535a2ee79ea10c1f7ce6d22ee7307982ac50ec13bfc45421dfeb22e2ba34623' 
  AND token = 'xIKG2dYuRny/LrYJtbNSSGx/qp7c58YP8125T2SogyA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}