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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e1da6990f0120d42c4e34f485ce3c24e3d05e61f98079d88bdaa7bea6c9cfa49' 
  AND token = 'eNkMxHsnmNxdQo926ho11zmULNtvcpnJCTi0p3zRsuo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}