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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e33ced0eee3a5927cad3a9bed62e12340891da68b3e3d29934122df7adb193b1' 
  AND token = 'RXivM9oKg4TY4GMWxe4T8oLDNToA43LTPKSsnCFU280=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}