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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4b5dad59501c28670fc057f1e3980114386bb5fe92e9c1b40fe64d913b0904cd' 
  AND token = 'mX5+NbuY0JpQ0/cqTQwP8uhZLMhoZPLeHsBo1rLOl8c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}