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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '665ecfc3555945a0019fc5e4f822e37ce7f23eddd3b3e6b496b21ef7bb4f7c47' 
  AND token = 'L77DoyOYCdP3W6DyPRkXEBCdqzE1W3aOZ/GE/UExlhY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}