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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f23c33d444b508eb789ebe8ae2a70924e26e22b124966c12465052d92034e927' 
  AND token = 'lPvypiSLPkYhWB5OWDV5nB+3FZwpviaXd2MIFPHDCs0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}