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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8c5ec17764c78baefbb9dac5a8eb082dace283995d49b19d68b6b86c78f77079' 
  AND token = '99TG9uHY7P4PY0LbOaed1zPnyRvLTFI/c1wIYUKuk3o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00051

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}